4dtv, four-fold synonymous (degenerative) third-codon transversion, has replaced the Ks to estimate homologue distance at neutral sites.
Is there any script/tool to calculate pairwise 4dtv for two homologous gene pairs?
Mr. Tao Shi,
It is not the subject of my concern, however you can refer to this article with doi: 10.1016/j.molp.2016.04.016
https://www.sciencedirect.com/science/article/pii/S1674205216300533
where 4dtv analysis is performed and suggested link of useful perl/python scripts (github link below).
https://github.com/tanghaibao/bio-pipeline
Hope this will be helpful.
Do you have the script? I did not find the scripts in https://github.com/tanghaibao/bio-pipeline .
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