In the 1960's Hexachlorobenzene (HCB) caused mass intoxications a.o. porphyria in humans in Turkey.

Consult the FAO/WHO monographs for more details on all pesticides.

http://www3.epa.gov/airtoxics/hlthef/chlordan.html

http://www.atsdr.cdc.gov/toxprofiles/tp35-c3.pdf

Hi, See below for some examples for DDT and these more recent publications:

Environ Int. 2015 Sep 25;85:206-212. doi: 10.1016/j.envint.2015.09.004. [Epub ahead of print]

Prenatal DDT and DDE exposure and child IQ in the CHAMACOS cohort.

Gaspar FW1, Harley KG1, Kogut K1, Chevrier J2, Mora AM3, Sjödin A4, Eskenazi B5.

Dichlorodiphenyldichloroethylene exposure during the first trimester of pregnancy alters the anal position in male infants.

Torres-Sanchez L, Zepeda M, Cebrián ME, Belkind-Gerson J, Garcia-Hernandez RM, Belkind-Valdovinos U, López-Carrillo L.

Ann N Y Acad Sci. 2008 Oct;1140:155-62. doi: 10.1196/annals.1454.004.

PMID:

18991914

Similar articles

Select item 17272288 2.

In utero exposure to the antiandrogen 1,1-dichloro-2,2-bis(p-chlorophenyl)ethylene (DDE) in relation to anogenital distance in male newborns from Chiapas, México.

Longnecker MP, Gladen BC, Cupul-Uicab LA, Romano-Riquer SP, Weber JP, Chapin RE, Hernández-Avila M.

Am J Epidemiol. 2007 May 1;165(9):1015-22. Epub 2007 Jan 31.

PMID:

17272288

Free PMC Article

Article Chronic nervous-system effects of long-term occupational exp...

Article Association between maternal serum concentration of the DDT ...

Hi Susan

The kepone (chlordecone) has caused acute toxicity in workers of the Hopewell plant, leading to the ban of this organochlorine in the USA, in the 1970's

until now environmental pollution is though to cause hormone-like disorders and pathologies in the Caribbean

some paper deal with this topic

Adir, J., Y. H. Caplan, B. C. Thompson (1978). "Kepone serum half-life in humans." Life Sciences 22(8): 699-702

Boylan, J. J., J. L. Egle, P. S. Guzelian (1978). "Cholestyramine: use as a new therapeutic approach for chlordecone (kepone) poisoning." Science 199(4331): 893-5

Cannon, S. B., J. M. Veazey, Jr., R. S. Jackson, V. W. Burse, C. Hayes, W. E. Straub, P. J. Landrigan, J. A. Liddle (1978). "Epidemic kepone poisoning in chemical workers." American Journal of Epidemiology 107(6): 529-37

Cohn, W. J., J. J. Boylan, R. V. Blanke, M. W. Fariss, J. R. Howell, P. S. Guzelian (1978). "Treatment of chlordecone (Kepone) toxicity with cholestyramine. Results of a controlled clinical trial." New England Journal of Medicine 298(5): 243-8

Martinez, A. J., J. R. Taylor, P. J. Dyck, S. A. Houff, E. Isaacs (1978). "Chlordecone intoxication in man. II. Ultrastructure of peripheral nerves and skeletal muscle." Neurology 28(7): 631-5

Taylor, J. R., J. B. Selhorst, S. A. Houff, A. J. Martinez (1978). "Chlordecone intoxication in man. I. Clinical observations." Neurology 28(7): 626-30

Larson, P. S., J. L. Egle, Jr., G. R. Hennigar, R. W. Lane, J. F. Borzelleca (1979). "Acute, subchronic, and chronic toxicity of chlordecone." Toxicology and Applied Pharmacology 48(1 Pt 1): 29-41. http://dx.doi.org/10.1016/S0041-008X(79)80005-8

Fariss, M. W., R. V. Blanke, J. J. Saady, P. S. Guzelian (1980). "Demonstration of major metabolic pathways for chlordecone (kepone) in humans." Drug Metabolism and Disposition 8(6): 434-8

Saunders, L., P. Kadhel, N. Costet, F. Rouget, C. Monfort, J.-P. Thome, L. Guldner, S. Cordier, L. Multigner (2014). "Hypertensive disorders of pregnancy and gestational diabetes mellitus among French Caribbean women chronically exposed to chlordecone." Environment International 68: 171-176. http://dx.doi.org/10.1016/j.envint.2014.03.024

Kadhel, P., C. Monfort, N. Costet, F. Rouget, J.-P. Thome, L. Multigner, S. Cordier (2014). "Chlordecone Exposure, Length of Gestation, and Risk of Preterm Birth." American Journal of Epidemiology 179(5): 536-544. http://dx.doi.org/10.1093/aje/kwt313

Boucher, O., M.-N. Simard, G. Muckle, F. Rouget, P. Kadhel, H. Bataille, V. Chajes, R. Dallaire, C. Monfort, J.-P. Thome, L. Multigner, S. Cordier (2013). "Exposure to an organochlorine pesticide (chlordecone) and development of 18-month-old infants." Neurotoxicology 35: 162-168. http://dx.doi.org/10.1016/j.neuro.2013.01.007

Dallaire, R., G. Muckle, F. Rouget, P. Kadhel, H. Bataille, L. Guldner, S. Seurin, V. Chajès, C. Monfort, O. Boucher, J. P. Thomé, S. W. Jacobson, L. Multigner, S. Cordier (2012). "Cognitive, visual, and motor development of 7-month-old Guadeloupean infants exposed to chlordecone." Environmental Research 118: 79-85. http://dx.doi.org/10.1016/j.envres.2012.07.006

Clere, N., E. Lauret, Y. Malthiery, R. Andriantsitohaina, S. Faure (2012). "Estrogen receptor alpha as a key target of organochlorines to promote angiogenesis." Angiogenesis 15(4): 745-760. http://dx.doi.org/10.1007/s10456-012-9288-7

Multigner, L., J. R. Ndong, A. Giusti, M. Romana, H. Delacroix-Maillard, S. Cordier, B. Jegou, J. P. Thome, P. Blanchet (2010). "Chlordecone exposure and risk of prostate cancer." J Clin Oncol 28(21): 3457-62. http://dx.doi.org/10.1200/JCO.2009.27.2153

Hi, See below for some pesticide :  more recent publications:

Article Pesticides increases soil fertility but compromises human fe...

Please see the following RG links.

Article Review Article. Organochlorine pesticides, their toxic effec...

Article Toxic Effects of Organochlorine Pesticides: A Review (OPEN ACCESS)

Check please

Article Organochlorine Pesticides and Male Genital Anomalies in the ...

Article Organochloride pesticides modulated gut microbiota and influ...

Article Case–control study of PCBs, other organochlorines and breast...

https://sci-hub.tw/10.2307/25549614

asma

Check our research letter: 10.1016/S0140-6736(00)04249-5

Plus for example.. :

doi: 10.1016/j.envint.2019.105049. Epub 2019 Jul 27.PMID: 31362153

doi: 10.1016/j.ijheh.2016.05.001.