1: Registration is not mandatory but has benefits including "promotes transparency, helps reduce potential for bias and serves to avoid unintended duplication of reviews":
Article Why prospective registration of systematic reviews makes sense
2: You can register in PROSPERO or Figshare, Github, even ResearchGate, etc. PROSPERO criteria for accepting a review:
I have seen non clinical and non human systematic reviews in PROSPERO.
3: You can publish the protocol of your systematic review before or after registration but journals prefer to publish after registration.
4: Journals who publish the protocols of systematic reviews are not free most of the times.
5: If you work with Cochrane on a clinical review you do not have to register your review in PROSPERO because Cochrane will do that but the process of the review might be longer.
You should always register the protocol of any study and systematic review. PROSPERO and Cochrane should be sufficient. Can you really trust any study that has not published version 1 of its protocol? Cochrane would argue that if a study has not published its protocol and registered itself that it is of High risk of bias.
Publishing protocol is improtant to improve the transparency and prevent duplication of your work. The JBISRIR is a good place for you to register your review before publishing and the website is
I am wondering what lies behind Sami's question? As others mention there are advantages of registering a review although (to my mind) the argument is less compelling than it is for primary research. However, it avoids duplication of effort and subsequent selective reporting of outcomes etc.
The Cochrane Library publishes protocols of reviews that are undertaken under it's own auspices (in simple terms health, treatment effectiveness) and using it's own methods, so that's not suitable for everything. Prospero requires a health outcome. Others have mentioned things like the Joanna Briggs Institute but I think that's quite similar to the Cochrane collaboration (focus on health and comes with it's own set of 'methods').
A couple of the replies above mention things i am not familiar with (https://www.researchregistry.com/ & https://osf.io/ but look like good general alternatives. Other options include publishing although generally this involves a gold open access fee in the sorts of journals most likely to publish protocols.
I can reccomend Center for Open Science OSF (www.osf.io). It is free of charge, besides you can generate DOI and link it with publication. It is also worth noticing that your work is visible via google.
It is also possible to publish the protocol as a paper in a journal (with a peer review) or even here in the RG or OSF (without a peer review). I think the most important point for transparency is that the previous design of the SR is available
Yasser Sami H. Abdel Dayem Amer - I am not sure if you were giving an answer or asking the question, but for the benefit of others, the description from the site gives a good answer:
PROSPERO is an international database of prospectively registered systematic reviews in health and social care, welfare, public health, education, crime, justice, and international development, where there is a health related outcome. Key features from the review protocol are recorded and maintained as a permanent record. PROSPERO aims to provide a comprehensive listing of systematic reviews registered at inception to help avoid duplication and reduce opportunity for reporting bias by enabling comparison of the completed review with what was planned in the protocol.
Have you looked into the Joanna Briggs Institute? They are specifically interested in health research and health outcomes, and they do offer registration of systematic reviews. https://jbi.global/systematic-review-register
It depends on the area of your topic of interest there are some journals that accept protocols, sometimes it may not be stated on their website but you can always e-mail them and ask. E.g., BMJ open, BMC, EJCC and many others...
JBI also publishes protocols for systematic reviews...