Is there any online server available for virtual screening of inhibitors against an enzyme ??

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Anu Manhas

There are scores of online server available for the virtual screening like ZINC, SPECS, ChEMBL, Dock blaster and more. You can google it.

Regarding the validation of Insilico methods; if it is pharmacophore generation, then go for ROC, Gunner Henry, etc and if Docking, go for redocking, correlation plot, ROC and more.

Mohsin Yousuf Lone

Please find the link for the list of software's exploited for docking based virtual screening:

https://www.researchgate.net/post/Can_anyone_recommend_a_docking_program

For the validation go with the suggestions provided by Anu Manhas

Sargol Mazraedoost

Hello

CASTp, Autodock vina, Swissmodel, Qsite, Chimera, RasMol or JMOL, MOE, BIOVIA Discovery Studio.

Check in these links. It might help you.

https://www.click2drug.org/

Good Luck.