ARV drugs, treatment regimens (drug combinations) and formulations for children have remained limited especially for use in resource constrained settings in spite of increasing availability for adult therapy. A few drugs have been approved for use by the FDA in the USA, but based on research data that did not include "resource-limited" settings.  There is still a gap in ART coverage in children that resides largely in these constrained settings, which could constitute a serious challenge in the effort to attain not just country/regional, but global targets as well.

Any evidence from available literature or clinical experience?

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