progesterone related drugs used by women and their metabolites in form of glucuronides and sulphates and enters to environment. Are they have any affect on human reproductive health
High progesterone levels in men cause an increase in estrogen production, which can lead to a number of problems. According to MayoClinic.com, excessive estrogen is linked to heart conditions, depression and fatigue. Higher estrogen levels can lead to an enlarged prostate. Other side effects of an increase in estrogen caused by high progesterone levels include prostate inflammation, urination difficulties and erectile dysfunction.