Dear all,
My question is about Inducible hypoxia in vivo (mouse model). I'm looking for some chemicals that can induce the pathway of hypoxia or some other techniques. If you now know something or want to share some papers I will appreciate.
Thanks
Dear Stefano!
Please you look at following protocol:
Article In Vivo Model for Testing Effect of Hypoxia on Tumor Metastasis
4. Femoral Artery Ligation (FAL) for Inducing Hypoxia
The following article may help you in devising chemical method to induce hypoxia.
Article: The use of cobalt chloride as a chemical hypoxia model:
November 2018 , Journal of Applied Toxicology 39(8)
- DOI: 10.1002/jat.3749
Hi,
In place of Cobalt Chloride, you can also use the Cyanide.
https://www.sciencedirect.com/science/article/pii/B9780123851574002578
Article Promising effects of xanthine oxidase inhibition by allopuri...
Hello Stefano, please check our paper!
Stefano Piacentini, you can use Cocl2 as hypoxia mimicking agent
A new model of retinal photoreceptor cell degeneration induced by a chemical hypoxia-mimicking agent, cobalt chloride
Journal Brain research
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