Is there a TCR transgenic mouse model on FVB background that produce CD8+ T cells specific to e.g. ovalbumin or hemagglutinin?

07 October 2021 0 655 Report

I am planning an in vitro mouse tumor cell/T cell co-culture assay. Tumor cells are derived from a GEMM that was generated in FVB mice. I am now searching for an transgenic TCR FVB mouse model that produce CD8+ T cells specific to an antigen like ovalbumin or hemagglutinin. There are comparable models with ovalbum-specificity (OT-I mice in C57BL/6 strain) and hemagglutinin-specificity (Clone 4 mice in BALB/c strain). Can anyone recommend a suitable transgenic TCR FVB model?

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