Is that possible to sequence a target directly from extracted genomic DNA (~ 300 Mb) without the previous PCR amplification step?

I have problems to amplify by PCR (using two primers) an specif target from extracted genomic DNA to produce purified amplicons to submit it to the sequencing PCR. But I know one of the primers...

09 December 2019 2,007 2 View

Please where can I access study materials that will help me in my project work to monitor adverse drug reactions of isoniazid in HIV patients on IPT?

Isoniazid preventive therapy has been recommended for all HIV patients with latent TB in Nigeria, but there is no little or no monitoring of adverse drug reactions. Therefore the need to monitor...

17 August 2018 2,252 2 View

Dear colleagues is there any codes for estimating Bilateral FDI using the gravity model in Stata, specifically the fixed effect estimation?

I am looking at the determinants of bilateral FDI using the gravity model

22 May 2016 7,476 3 View

No title

22 April 2016 5,362 18 View

The SRMR is 0.141 in CFA but other indices are ok. What is the implication?

I have run a CFA to confirm the factor structure of a questionnaire The CFI and TLI are larger than 0.95, RMSEA is below 0.06. Relative chi-square is close to 2 However, the SRMR is 0.141...

20 April 2016 7,055 7 View

How to compare 2 samples recruited with different sampling methods?

If I want to compare characteristics of 2 groups of patients, one group is recruited from a random sample of the general public while another group is from a sample with a fixed gender (male to...

26 February 2021 3,526 3 View

Do you consider undergoing a structure literature review / Meta analysis and getting numerical findings sort of quantitative method?

I am looking for a classification of the research methods included in literature review papers or Meta analysis ones .

22 February 2021 1,131 4 View

Can I do two kinds of mixed method in explanatory research?

Dear distinguish professors and scholars, I have a research in measuring two kinds: think tank capacity and research impact on policy. Can I do two kinds of mixed methods in order to find, "Is...

20 February 2021 6,897 1 View

How to analyse a (perceptual) study using differing/comparable sets of stimuli?

I plan on running an online perceptual experiment that has, let's say, 100 unique video stimuli altogether. Since these are too many to be rated by every participants, I would like to present the...

15 February 2021 7,444 2 View

How to analyse a split-plot design in stata ?

I have run an split-plot design experiment evaluating the efficacy of a treatment (with 3 whole plots and 4 sub-plots), and I am planning to analyse the collected data in Stata. However, I do...

14 February 2021 7,800 7 View

Can I use a likert survey for criterion sampling in a qualitative study or would that make it mixed methods?

I am doing a phenomenographic study on the reading experiences of avid v. Neutral v. Non-Readers. If I use a likert survey to criterion sample for participants, does that make it a mixed method...

09 February 2021 8,594 3 View

How to create the context-mechanism-outcome configuration (CMOc) in the realist methodology?

In the realist methodology (especially by Raymond Pawson et al), the CMOc is a common structure to explain what works, for whom, in what circumstances, and why? I'm always asked about the...

08 February 2021 2,792 1 View

Recommendations for sample size in visual qualitative research (using children's drawings)?

Hi everyone! Asking for a little help, if I may. I am working on a research project, where I aim to analyse children's drawings about Covid-19. I am fairly new to using visual data in qualitative...

07 February 2021 9,530 3 View

How do I create a categorical variable, level of exposure, and a dummy dichotomous, yes-no, variable for the Harvard Trauma Questionnaire Part 1?

I am using the Harvard Trauma Questionnaire (HTQ) Trauma Events scale (original version) that has 17 items (17 different traumatic events) with 4 response options, indicating 4 levels of exposure:...

04 February 2021 1,509 3 View

How to report path analysis / SEM with Yuan-Bentler correction from R output?

Dear all, I am currently writing my master thesis where I am analysizing my data using path analysis and SEM in R (lavaan package). Now that I like to write up my results, I am struggling with...

04 February 2021 8,993 2 View