Has anyone observed a quality variation during antibacterial susceptibility testing like in disk diffusion assay?
Oxoid™ vs Other brands?
Nope, never had any issues.
I used Sigma, Oxoid and I think Roth (different labs, different suppliers) on several media. Always seemed the same.
If worried, you can check the recipe on the bottle
Though the main composition of Muller Hinto Broth (MHB) is same from most of the manufacturers, However, the Oxoid MHB contains high concentration of dehydrated beef infusion. WHO recommends the Oxoid MHB for testing microbic sensitivity test
WHO (1961) Standardization of Methods for Conducting Microbic Sensitivity Tests. Geneva. Tech. Rep. Ser. No.210
The following research article may provide you more information, have a look
https://www.ncbi.nlm.nih.gov/pubmed/?term=J.+Clin.+Path.+62.+113-117.
Best
In general all medias made by different manufacturers are slightly different, even media from batch to batch production with the same manufacturer can be slightly different. Ingredients used to make the media have different grades. Basically its down to validation and comparing the media recipe in an ISO method with that of the manufacturer
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