I have carried out a dietary questionnaire for the nutritional prevention of colorectal cancer, so I evaluate the amount of fiber consumed daily using a simple food frequency questionnaire. As well as the consumption of red meat and processed meat in order to offer nutritional advice adapted to the personal consumption of patients at risk of colorectal cancer. Patients are seen again a few months after to re-evaluate their consumption. Although most patients increase their fiber intake, it is quite disappointing for them not to reach the recommended 30g of fiber per day or at least 25g for women or the elderly. I was therefore wondering if there was a curve showing the health benefits or more specifically colorectal cancer benefits as a function of fiber intake. This would allow me to estimate the percentage benefits on overall health or colorectal cancer of an increase in fiber intake. Thank you in advance.
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Dietary fibre can definitely protect against development of colorectal cancer. In populations with low fibre intake , doubling the fibre intake may reduce the risk of colorectal cancer by upto 40%. There was the “EPIC” study which was done on 5 hundred thousand participants in Europe in nineties. This was published in Lancet. There was definite risk reduction.
Please go through the article, it may help you in your study.
EPIC study
June 2003. Lancet 361(9368):1496-501
DOI:10.1016/S0140-6736(03)13174-1 Pubmed
The average adult only eats 15 grams of fiber per day.
Women need 25 grams of fiber per day, and men need 38 grams per day, according to the Institute of Medicine.
Dietary "vegetable natural fibre" has definitely medicinal effects in prevention of multitudes of health issues including CRC, cardiac diseases, hepatic disorders, etc. Lot of work has been done but its implementation is lagging behind. This article is a good sign of its awareness programme. Continue ur good job.
"Human dietary intervention studies have also indicated that the modifying effect of dietary fiber on bacterial enzymes involved in the production of putative colon tumor promoters depends on the type of fiber consumed. Dietary wheat bran, but not oat or corn bran, significantly decreased the levels of several tumor promoters in the colon, independent of stool bulk." Am J Med. 1999 Jan 25;106(1A):16S-19S
" The study demonstrates that the lipid fraction of wheat bran has strong colon tumor inhibitor properties." Cancer Res. 2000 Sep 1;60(17):4792-7.
" Dietary fibre intake may impact gut microbiota composition, particularly class Clostridia, and may favour putatively beneficial bacteria such as F. prausnitzii. These findings warrant further understanding of diet-microbiota relationships for future development of colorectal cancer prevention strategies." Br J Nutr
. 2018 Nov;120(9):1014-1022.
" The optimization of fibre within our diets represents an important public health strategy to improve both metabolic and overall health. If implemented successfully, this strategy would likely result in substantial future health benefits for the population. " Nutrients. 2020 Oct 21;12(10):3209.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6560290/#!po=1.66667
Hope you may find your answer here in the above link
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