Is the complications in deceased and living donor kidney transplantations are different?
The basic medical and surgical complications in renal transplantation are common to both live donor and deceased donor transplant. however, deceased donor transplants have a few exceptions mainly with regard to the prolonged cold ischaemia times and preservation injuries pertaining to the extra time inbetween harvest and implantation
1. Higher risk of ATN and delayed graft function
this can be due to prolonged cold ischaemia time as well as ischaemic injury to the donor kidneys prior to and during the organ harvesting (unlike a live donor situation)
2. Higher incidence of ureteric complications (stricture / dehiscence)
Even though the incidence of these ureteric complications are minimal in current practice, ischaemic injury can be more on the cadaveric ureters in deceased donor transplants
Following on from Nalaka's answer I would also like to add that the rates of ureteric complications as well as vascular complications post renal transplantation are also related to the use of extended criteria deceased donor kidneys along with the cold and warm iscahemic times -
https://www.intechopen.com/books/understanding-the-complexities-of-kidney-transplantation/surgical-complications-of-renal-transplantation
Hence most programmes have selection criteria in place when it comes to accepting deceased donor kidneys from extended criteria donors (including donation after circulatory death) as well as thresholds for when it is acceptable to transplant akidney should it have been injured during the surgical retrieval process.
The complications difference is due to the basic difference between live and cadaver donor risks and not on the treatment or operative component.
In cadaver donors one can harvest a larger portion of the renal blood vessels as compared to live donor and hence may pose some difficulties in the anastomosis of the blood vessels in the recipient.
Thank all researches whom participate in this question😊😊😊😊😊
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