Adopting a carbohydrate intake deprivation diet such as the ketogenic diet would lead to normalization of plasma glucose markers, but does that reflect the normalization of Beta-cell dysfunction in type 2 diabetes?
Blagosklonny MV. The mystery of the ketogenic diet: benevolent pseudo-diabetes. Cell Cycle 2019;18(18):2157-2163. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6738531/pdf/kccy-18-18-1644765.pdf
Bravo-San Pedro JM, Sica V, Kroemer G. Pseudodiabetes-not a contraindication for metabolic interventions. Cell Death Dis 2019;10(10):765. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787197/pdf/41419_2019_Article_2007.pdf
Ellenbroek JH, van Dijck L, Töns HA, Rabelink TJ, Carlotti F, Ballieux BE, de Koning EJ. Long-term ketogenic diet causes glucose intolerance and reduced β- and α-cell mass but no weight loss in mice. Am J Physiol Endocrinol Metab 2014;306(5):E552-8. https://journals.physiology.org/doi/full/10.1152/ajpendo.00453.2013
Kindly check https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520897/
I would like to share with you my letter introducing the concept of diabetes pseudo-reversal.
https://authors.elsevier.com/a/1c14C5KvDK8GzW