Ropivacaine is safe in renal failure. Although a metabolite of
ropivacaine (pipecoloxylidide) may accumulate in plasma during
long-term postoperative infusions, in particular in patients with
coexisting low non-renal elimination, its systemic toxicity is
markedly less than ropivacaine.
Ref
Pere PJ, Ekstrand A, Salonen M, et al. Pharmacokinetics of ropivacaine
in patients with chronic renal failure. Br J Anaesth. 2011;106(4):512–21.