There are certain locations on the genome where a mutation might happen at a higher incident. However, in bacteria the active genes are/make up almost the entire genome where the active genes in humans makes' up only 5% of the human genome. Can we say: that a preliminary ratio for the difference in mutations in active gene loci, for example, between bacteria and human is as the difference between the ratio 1:1 and 1:0.05. This difference is due to the fact that intros also play a role in diluting mutations which otherwise will be affecting active genes; the more introns there are in a given genome the lesser the chance that the active genes loci will be affected with a mutation?
In his book: David P. Clark, Nanette J. Pazderink, title: Biotechnology, update edition, academic cell, ch 21, 22, does imply the above.(?) since it is known that bacteria mutate faster. (?)
molecular biology of the cell, 5th ed., the problems book, john wilson, tim hunt, p. 487, ch: 1, cells and genomes, qus./answer 1-2. ..."in single-celled organisms the genome is the germline and any modification is passed on to the next generation"....
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