Dear Soomro, the SPR sensor with organ on chip platform is slowly blooming. Although, there are several reports of SPR biosensor, however, organ on chip is still at its nascent stage. It requires precise integrated photonics design. Anyways, I am attaching some relevant content for your help.
a)https://www.ncbi.nlm.nih.gov/pubmed/28265064
b) Article Dynamic Monitoring of Mechano-Sensing of Cells by Gold Nanos...
c) https://books.google.co.in/books?isbn=3319111280