In order to assay PD-Tox of my compound of interest I would like to do I suppressed the immune system of rats before injecting the human cancer cells to induce the tumour.
Please suggest me how can I establish athymic rat?
Thank you Dr. Goodwin. We already have done efficacy study on nude mice. now we would like to do preclinical study on rat. In order to establish cancer on rats we need immunosuppressed rat.