I am planning a transplantation experiment. My donor cells would be from DBA/1 strain. Since there is no CD45 allelic variants (Ly5.1 or Ly5.2) in DBA strains, I would like to know whether it is possible to make F1 hybrids of DBA/1 X B6-SJL and transplant (maybe?) DBA/1 cells to F1 hybrids.
Note: I have an option to use immunodeficient strains but I am trying to see whether I can avoid it.
Any leads would be much appreciated. Thanks :-)