Is it possible characterize polysaccharides and interpret the structure completely when using MALDI TOF MS system ?

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Robin Joshi

Yes you can do. People studied oligo and polysaccrides characterization using MALDI-TOF-MS.

You can also go for LC-MS-MS or any other mass spectromtry techniques.

Byju Ponnana

Thanks Robin Joshi, How can we know the linkage between the monomers using MALDI MS, I am purified the polysaccharides using molecular weight cutt off membrane and i think it is almost pure. In TLC it is not vissible clearly. I think it is enough for NMR studies .. Correct..? I will take the MALDI TOF MS and NMR which is enough for the characterization ..?I have LC MS in my lab but it is for molecular weight up to 2000amu.