Are there any article in this issue?
There is another thread about this question:
https://www.researchgate.net/post/is_it_possible_to_use_skin_patch_for_insulin_delivery_in_diabetic_people
Insulin is a macromolecule so naturally it can't pass through skin. But researchers are working on techniques to let it pass.
Here Are some articles that may help you:
http://link.springer.com/article/10.1023%2FA%3A1015869420159?LI=true
http://onlinelibrary.wiley.com/doi/10.1002/jbm.a.35869/full
http://www.tandfonline.com/doi/abs/10.3109/10717544.2016.1155243
https://ecommons.cornell.edu/handle/1813/43906
http://link.springer.com/article/10.1023/B:PHAM.0000029282.44140.2e
Dear Neda
Check out this:
http://www.diabeticadvocate.com/2013/04/insulin-cannot-be-absorbed-through-skin.html
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