Recent proof relates the COVID-19, SARS-CoV-2 affecting Orf8 and Hemoglobin, together with the clinical presentation of patients (as high altitude disease).
It is the intent of this Forum to make a discussion of the multisitemic disease of COVID-19 and all findings by researchers, from the respiratory tract infection, the Central Nervous system, Mulclesqueletal, Renal, Hematologic and Hepatic infections to form a COVID-19 Syndrome with a wider scientific view.
Please give us your findings to discuss. As an author it is my theory this is not a respiratory disease only but a multisistemic disease.
Intravascular Diseminated Coagulation has been found in COVID with a higher rate in all patients, and ventilator neumopathy. Experienced physicians add their experience so that all can share.
good point of discussion, as more and more is written about this disease things will be clarified more.
but being a virus it can affect many body systems , in relation to blood it may release free iron and cause tissue damage. we will wait abit before concluding that this is a hematopoetic virus
No doubt that Covid 19 is primarily a disease of respiratory system. 2ndarily it may affect multiple systems including hematological, like development of DIC, VTE, PE etc. However, most of these 2ndary effects are, most likely, due to hypoxia due to respiratory disease rather than direct viral attack.
I think that there is a direct impact on hemoglobin. At presentation on hospital day 1, why most patients have low Hb?
I think it is right an avenue of knowledge worth exploring.
Do you know the work by Prof. Gómez Moreno (Ángel Gómez Moreno (Universidad Complutense de Madrid), "Coronavirus, Population Genetics, and Humanities", Mirabilia, 30 (2020, 1): Special Issue: https://www.revistamirabilia.com/sites/default/files/pdfs/01._gomezmoreno.pdf ).
But, I think we need the contributions from a wide shared knowledge from lots of disciplines.
A world wide pandemic needs earn solutions from a world wide knowledge contributions.
Do you know, my colleagues, about any more works in this same or similar approach?
My so many thanks