In plant-pathogen interactions, horizontal/ lateral gene transfers are well known to challenge each other. But, these are results of 'transfer of biosynthetic machineries' (operons, gene clusters, repetitive elements etc.) as a result of 'physical transfer' during the course of evolution. But, does this interaction between plant and it's pathogens leave 'signatures' (patterns that mimic a defense response, circadian patterns, adaptive mutations in genes, suppressions, leading to super-active promoters etc.) in genes, proteins, inter-genic regions in the forms of signatures that is tracable using molecular techniques or computational efforts ? If yes, then how to trace these signatures and assign them to specific interactions (beneficial vs. harmful bacteria/ fungi/ nematodes )?