Can we think to change the A type group blood sample into B type or O type (in vitro)?or B type into A or O type. or O type into A or B type. There is little difference between antigenic determinants ( glycoprotien) of the ABO blood group system.
1. N-acetylgalactosamine at terminal of glycoprotein in A type
2. galactose at terminal of glycoprotein in B type
3. neither N-acetylgalactosamine nor galactose at terminal of glycoprotein in O type.
I remember hearing about progress in converting type B to type O. This would not be very helpful since not very many people are type B. The only useful change would be type A to type O. But I have not seen any research on this lately. Those small differences
if it goes to be interchanged then how it will help or what benefits will be.
in these days if only RBCs is separately provided, will it help?
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