Dear Maria,

These data below should help:

Which is more harmful acriflavine or hydrochloride?

Infobox references. . Acriflavine ( INN: acriflavinium chloride) is a topical antiseptic. It has the form of an orange or brown powder. It may be harmful in the eyes or if inhaled. It is a dye and it stains the skin and may irritate. The hydrochloride form is more irritating than the neutral form. It is derived from acridine.

Acriflavine - Wikipedia

en.wikipedia.org/wiki/Acriflavine

Which is more harmful in the eye acriflavine or hydrochloride?

Acriflavine ( INN: acriflavinium chloride) is a topical antiseptic. It has the form of an orange or brown powder. It may be harmful in the eyes or if inhaled. It is a dye and it stains the skin and may irritate. The hydrochloride form is more irritating than the neutral form.

Acriflavine - Wikipedia

en.wikipedia.org/wiki/Acriflavine

How is acriflavine used in the treatment of cancer?

Acriflavine is used in biochemistry for fluorescently labeling high molecular weight RNA. It is used as treatment for external fungal infections of aquarium fish. In an animal model, acriflavine has been shown to inhibit HIF-1, which prevents blood vessels growing to supply tumors with blood and interferes with glucose uptake and use.

Acriflavine - Wikipedia

en.wikipedia.org/wiki/Acriflavine

How is acriflavine used to treat hepatocellular carcinoma?

Antitumor activity of acriflavine in human hepatocellular carcinoma cells. Lee CJ (1), Yue CH (2), Lin YY (3), Wu JC (4), Liu JY (5). Patients suffering from advanced hepatocellular carcinoma can generally be treated only by targeted therapy to achieve a survival rate that lasts a few months more than that achieved with conventional therapy.

Antitumor activity of acriflavine in human hepatocellular ...

www.ncbi.nlm.nih.gov/pubmed/24982368

Hello

Yes, Acriflavine and Acriflavine Hydrochloride are the same in terms of their anti-cancer activity in vivo and their stability in physiological solution.

Acriflavine Hydrochloride is the salt form of Acriflavine. Drugs are often chemically made in their salt form in order to enhance drug solubility, boost its absorption into the bloodstream as well as increase its effectiveness. To bring about a therapeutic effect, drug molecule has to be absorbed. The salt form of the drug provides higher concentration in solution than its non-ionized form. This is the reason why more than 50% of all drugs exist in their salt form like hydrochloride or sulfate salts.

I hope this is helpful.

Best Wishes.