In docking analysis whether itis scorrect to take the grid values from discovery software?

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Kavita Patel

If you can see the grid box is covering the desired space (blind docking: whole protein or specific: active site residues), then yes.

if you are performing on autodock , so its better to check the grid box position before running the docking.

Janaranjani Dhanapal

Thank you mam

Arunkumar R.

Yes, using grid values from Discovery Studio is appropriate if the grid box correctly encompasses the target region; whether for blind or site-specific docking, and its placement is properly verified in AutoDock before running the analysis.