The chemical absorption process carbon capture and separation technologies. This process comprises two stages: The absorption of CO2 into the solvent and the desorption, to regenerate the solvent and produce the high concentrated CO2 gas.Validated simulation models are essential for the scale-up of the chemical absorption process and they are typically validated using only data from one pilot plant. The simulation model of the desorption column can be built in ASPEN PLUS v8.6 validated using four experimental pilot campaigns using 30 wt% MEA. The desorbers in the different campaigns varied in the diameters, structured packing heights and packing types.