Hello everybody. Have you guys any experience with extrapleural pneumonectomy plus intraoperative hyperthermic chemotherapy perfusion in malignant pleural mesothelioma? Thank you! Have a good day!
We have lots of experience at penn Presbyterian with mesothelioma using photodynamic therapy you should contact Dr Sherman in pulmonary medicine at penn or Dr Friedberg at pennpresbyterian
The majority of the published literature comes from Dr. Sugarbaker. However, due to the issues from EPP on physiology and the such (lack of options when recurrence occurs) with HIPC (IHC), more and more the surgery of choice seems to be extended pleurectomy/decortication with or without an intraoperative adjunct (i.e.: PDT or HIPC) with the goal still being MCR. I would also direct you to the current SMART trial (Surgery for Mesothelioma After Radiation Therapy) which looks promising.