If there is no available similar study, how can determine the sample size of prospective cohort study?

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Bhogaraju Anand

Hi,

Refer to this article

https://online.stat.psu.edu/stat507/book/export/html/675

Basharat Hossain

https://sphweb.bumc.bu.edu/otlt/MPH-Modules/EP/EP713_CohortStudies/EP713_CohortStudies_print.html

Tadele Mekuriya Yadesa

In the equations to estimate sample size, you are required to have prevalence of the outcome in exposed and unexposed group; which you can get from any related study from similar setting else where. Or you assume OR of 2. But in either case you need to have an estimate of the prevalence of the exposure in the population to decide on unexposed:exposed ratio.