I work with female mice and I have this doubt. If they are all put together on the same cage, are all of them on the same estrous cycle stage?
If so, is there any literature that supports this?
I do not measure and/or calibrate estrous cycle because I do a protocol where I don't want the animals to be stressed by it.
Hi Raquel,
For a basic introduction to the McClintock Effect, see: https://en.wikipedia.org/wiki/Menstrual_synchrony
Although her work with female college students sharing a dormitory was never replicated, others repeated her work in non-human mammals:
Handelmann, Gail; Ravizza, Richard; Ray, William J (1980). "Social dominance determines estrous entrainment among female hamsters". Hormones and Behavior. 14 (2): 107–15. doi:10.1016/0018-506X(80)90002-1. PMID 7191403.
French, Jeffrey A.; Stribley, Judith A. (1987). "Synchronization of ovarian cycles within and between social groups in golden lion tamarins (Leontopithecus rosalia)". American Journal of Primatology. 12 (4): 469–78. doi:10.1002/ajp.1350120403. PMID 31973490.
Barbara McClintock later received the Nobel Prize for her fundamental discovery of mobile genes.
I hope this helps.
Peter
Hi Raquel,
I'm also searching for similar studies to synchronize the estrous cycle in female mice.
I found this article helpful. Hope it helps you.
Also let me know if you find a better method to synchronize the estrous cycles.
Best,
Tejas
Peter M Narins your answer definitely helped!
Do you know any literature where similar studies where performed in rodents? Similar to the study of Handelmann, Gail; Ravizza, Richard; Ray, William J (1980). "Social dominance determines estrous entrainment among female hamsters". Hormones and Behavior. 14 (2): 107–15. doi:10.1016/0018-506X(80)90002-1. PMID 7191403.
Regarding female reproductive entrainment in mice, I can seem to only find studies about circadian clock entrainment...
Thank you.
Raquel
Tejas Nikumbh what I want to know is if female mice that are on social interaction (together on the same cage) if we can call it that, are on the same stage of estrous cycle.
This study on hamsters that Peter M Narins referred suggests that.
Handelmann, Gail; Ravizza, Richard; Ray, William J (1980). "Social dominance determines estrous entrainment among female hamsters". Hormones and Behavior. 14 (2): 107–15. doi:10.1016/0018-506X(80)90002-1. PMID 7191403.
I just need to find a study in rodents...
I need to answer to a reviewers' question on an article regarding this matter.
Best regards,
Raquel
Peter M Narins hamsters are rodents! jesus christ!
You can see how tired I am!
And on the Wikipedia page there are also references of studies in rats.
Thanks again for your help!
Best regards,
Raquel
Hi Raquel,
One of my mentors used to say: "It's OK if you fall down, as long as you pick up something from the floor before you stand up." You did it! Good luck!
Peter
Hi
Yes, most of female mice will be on estrus cycle if they were in the same cages but not all...that depands on the age and prior cycle..... but mostly exposed to the same stresses so the cycle period will be in near periods
Hi Raquel,
I had this question for a different issue (in my case was knowing when are females synchronized in order to stimulate them and get timed-pregnant females). I found this article from JAX super useful, and maybe some paragraphs can help you (3) Group-house females and synchronize their estrous cycles prior to mating.)
https://www.jax.org/news-and-insights/jax-blog/2014/september/six-steps-for-setting-up-timed-pregnant-mice
Hope its useful!
Hi Raquel,
we had some sign for synchronization, however they were usually not in the same stage even being in the same cage. David
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