The reaction gave dark brown liquid product. Is this correct?
Can be liquid. Acquire a spectrum for confirmation.
Many thanks Dr. Kaufman for you answer, i will try to perform spectral analysis
Even I am preparing Schiff's base but is it possible to separate it for analysis ??
but Schiff's bases are sensitive to water if I add MeOH/H2O, water will shift my reaction back...
For alternative preparation see article below:
https://www.researchgate.net/publication/265959505_Synergism_of_Metal_and_Organocatalysis_in_Condensation_Reactions_of_Aromatic_Aldehydes_with_Anilines_Affording_Imines_Effect_of_Catalysts_on_the_Base_of_a_Supported_Cerium%28III%29_and_Proline
Article Synergism of Metal and Organocatalysis in Condensation React...
Gouda,
This reaction has been reported using toluene as a solvent and
1- AcOH and heat for 3 hrs, see
--- Srinivas, A. et al, Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 47B(5), 787-791; 2008.
2- p-MeC6H4SO3H (cat.), see
--- Kitagawa, Yukio Jpn. Kokai Tokkyo Koho, 08151352, 11 Jun 1996.
--- Rubio-Marques, Paula et al, Chemical Communications (Cambridge, United Kingdom), 50(14), 1645-1647; 2014.
--- Barluenga, Jose et al, Journal of the American Chemical Society, 131(11), 4031-4041; 2009
Also, this reaction was reported using CH2Cl2 (solvent) and MgSO4 for 18 hr at rt, see
--- He, Ruoyu et al, Journal of the American Chemical Society, 136(18), 6558-6561; 2014.
Good luck
Many thanks for you all, Prof. Dr. Adel Amer, Dr. Pavel Pazdera and Dr Azeem
You can use catalytic amount of PTSA (p-toluene sulfonic acid) in toluene as a solvent under reflux for 4-6 hrs.
Is There Any Feasible Method To Test The Efficiency Of Fluorescent Compounds Other Than UV Spectrometers ? Suggestions Would Be Appreciated !
02 March 2021 5,785 3 View
Dear all, I just saw this example in FB on the difference between laminar flow and turbulent flow. The flow from a pipe hits the sink and scattered. The flow from the pipe is characterized as...
02 March 2021 1,999 5 View
I am at the beginner level in drug design and drug discovery, and I am interested to learn more about this field. Which books are highly recommended to start from and gives me all essential...
02 March 2021 8,437 2 View
Could you please recommend some good journal that accept very long revie papers (approximately 6000+ words) in neurosurgery, cancer biology ?
01 March 2021 8,087 3 View
I want to differentiate between normal and abnormal movement. For this reason, I am looking forward to this type of dataset.
01 March 2021 9,485 1 View
Hello, I am writing a python script to generate my model and write the input file. The problem is I have 1000 elements in my mesh and I want to assign different material properties to each...
01 March 2021 9,511 3 View
Hello, Could you please share any interesting research explaining how to choose the number of hidden layers and nodes per layer in case of regression problems using ANN? Thank you, any help would...
01 March 2021 6,200 3 View
In Finite element software like ANSYS , there is difficulty in obtaining direct results of twisting of concrete members because SOLID65 which is the unique element designed to represent concrete...
26 February 2021 3,806 2 View
Hello everyone, I have some PHAs blended with fillers and nucleating agents, yet I don't know what kind of fillers or nucleating agents. The producer has shut down and there's no way to get in...
24 February 2021 1,356 8 View
We have deposited silicon carbide on carbon substrate using one PVD technique. Due to amorphous behavior of SiC at low deposition temperature, we performed heat treatment of those films at...
22 February 2021 2,072 3 View
How to calculate the RMSD values for a MD simulation using MOE?
07 August 2021 0 0 View
When I tried to energy minimization my system, I got fatal error as below. Fatal error: Atomtype opls_116 not found Although I've already added this line: ; include water #include "oplsaa.ff/spc.itp" to [molecultype] directive in my topology.
16 June 2021 0 0 View
What this unit identifies for the ion exchange capacity ca. 0.92 meq. g-1. I am a newcomer in the membrane area. I just started. I highly appreciate your help
08 May 2021 0 0 View
effect of double bond on the flexibility of polymers
07 April 2021 0 0 View
I am writing to request some information for making polymer color flakes. I would appreciate the help.
17 March 2021 0 0 View