Idebenone GC MS Mass spectrometry

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M. D.H. Prodhan

Dear Mauro Winkler,

Actually, for Idebenone, the HPLC or LCMS is more effective. The scientist are using HPLC or LCMS. Please have a look on the following link for solve your problem:

Article Development of UV Spectrophotometric method of Idebenone in ...

Article Determination of idebenone in plasma by HPLC/MS

Frank T. Edelmann

Dear Gabriel. Mauro Winkler thank you for your interesting technical question. I fully agree with M. D.H. Prodhan in that LC-MS / HPLC-MS is more useful in this case. Please also have a look at the following useful articles:

Monitoring of idebenone treatment in patients with Friedreich’s ataxia by high-pressure liquid chromatography with electrochemical detection

Article Monitoring of idebenone treatment in patients with Friedreic...

and

Stability-Indicating HPLC Assay for Determination of Idebenone in Pharmaceutical Forms

Article Stability-Indicating HPLC Assay for Determination of Idebeno...

Both articles are freely available as public full texts on ResearchGate.