Another way is to use a flow cytometer, if you turn the FSc threshold down and turn FSc area and SSc area on log you can count these particles, either via using a known ratio of counting beads or using a newer flow cytometer that counts particles per ul. It was a long time ago, but I seem to remember that unlabelled zymosan was around 165,000 particles per microgram. I also counted doublets as two particles, but it didn't make a big difference to particles per ul. You could also do the same for pHrodo bacteria.