I want to collect blood of normal mouse after treating it with Ag to check drug uptake, What is best way to collect blood?

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Renee R Donahue

There are many ways of collecting the blood. However, the simplest way would be via retro-orbital bleed. I have attached a methods paper outlining the procedure.

Engelbert Buxbaum

You will need permission from your animal use committee anyway, so it is best to contact them first about which methods are permissible at your institution and where to get any training necessary.

Bernhard H Monien

Hi, there is a paper "A good practice guide to the administration of substances and removal of blood, including routes and volumes", which helped me a lot in my time. The removal routes are explained in detail including the allowed upper limits of blood per time frame. Good luck!

Article A good practice guide to the administration of substances an...