I saw some research papers, they had been reported the DNA cleavage by using several type of nanoparticles. What is the use of DNA cleavage?

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Hugh J Byrne

DNA cleavage can be a (geno-) toxic response to radiation or a chemical agent, resulting in cell death. If this can selectively induced in cancer cells, then it can be used as a therapy.

Suresh K Ghotekar

Thanks Hugh

J. C. Tarafdar

@ Suresh, DNA cleavage is important in terms of its greater cell lethality than that from single strand cleavage.