6-hydroxy dopamine is an analogue of dopamine, which is used to induce parkinson's disease in animal models.
You can buy the compound from Regis Chemical Co. It would be extremely expensive to buy these models. First of all, do you want striatal or substantia nigra lesioned? Striatal injection of 6OHDA is not hard and you can learn the technique if you have the materials. Substantia nigra lesions are a little hard but can be done with practice. Rats are easier than mice to do.
@ Vernice I require striatal models for my research. it will be gr8 if u give me any link where striatal injection technique is demonstrated. kindly give the link of Regis Chemical Co.
There are several good methods for striatal lesions on PubMed. Search striatal lesions method and 6-OHDA. Regis site: www.registech.com
Good morning,
@Vernice Jackson-Lewis, PhD you wrote that they are expensive but could you suggest where i can buy these animal model please?
thank you a lot
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