Manuscript attached. SDM produces improvements in PERG, VA, and mesopic VA in every retinopathy including dry AMD and RP, in large part due to rescue of dysfunctional pre-apoptotic cells. I am confident DARC can show reversal of pre-apoptosis within days after SDM in any chronic progressive retinopathy including POAG. I have extensive data on all types of chronic progressive retinopathies (all neurodegenerations). I would like to discuss. Thank you [email protected]
Hi Jeff,
Encouraging results. We need to start doing microperimetry and other functional tests for both macula and retinal periphery.
IK
HI Igor! Nice to hear from you. I have a vast library of electrophysiology, microperimetry, mesopic visual fields and VA, mainly in non-DR (AMD, PR, Stargardts, etc).
What we see is:
1. SDM improves electrophysiology in every disease
2. The nature of the electrophysiology improvement is different and characteristic for each disease, as "reset" theory predicts.
3. Mesopic VA and perimetry improves in every disease.
4. By linear regression, the worse the pre-treatment findings for any measure, the more the improvement after SDM. Therefore, what we're seeing is restored function to previously non-functional (presumably pre-apoptotic) tissue (rescue). This is where I would expect DARC to show a reduction / disappearance of pre-apoptotic cells.
Best,
Jeff
- Badges
- Science topic
- Similar topics
- Linguistics
- Philology
- Classical Philology
- Manuscripts