I am resarching about β-Estradiol-dependent activation of the JAK/STAT by activated TNF-a in SH-SHY5Y cells but estradiol and jak-stat signaling relationship is little complicated to understand. Can you help me pelase?
This is an area of interest me. I am especially interest in insecticides that mimic estradiol, like heptachlor epoxide, activating the JAK/Stat pathway.
I can send a sample if you would like to test. The results would make a valuable contribution to the environmental community.