DNA/RNA G4 modelling and visualization tool ?

Hi, I would like to ask if anyone knows any tool for visualizing/modelling guanine structures (any RNA structures with Hoogsteen base pairing) based on sequences? I mean, if there is any...

02 November 2020 1,136 2 View

RNA isolation from blod: How to precipiatate excess protein before loading samples on silica column?

05 October 2017 3,989 2 View

Does anyone have any experience with rRNA depletion prior to transcriptome NGS?

16 October 2016 5,033 3 View

Is there any chance to melt Ni3Al dice (4,5 mm) on oxide ceramics in resistance furnace under Ar atmosphere ?

We used a lot of types of oxide ceramics based on Al2O3 and even used Spinel (MgAl2O4) ceramics - refractory concrete, which is even more stable, but Ni3Al always oxidized and not melt. We are...

09 February 2016 6,274 3 View

Is anyone interested in collaboration in the area inquiry-based learning?

I am interested to scientifically collaborate (projects, comparative research, training) on the topic of "inquiry-based learning" - IBSE. Anyone interested?

15 June 2015 5,340 3 View

Are there specific photographic techniques of surveys on for public perception of forest?

I prepare questionare surveys about public perception of forest within project http://rafa.frrms.mendelu.cz/en?lang=en. I have ideas about objectives of questionare, but Im looking for rules...

26 March 2015 2,524 3 View

What is the least drastic method to kill decapod crustaceans for subsequent preservation?

A variety of methods are used to kill decapod crustaceans for subsequent preservation. Generally the most acceptable method of killing crustaceans is to chill the animals to the insensitivity and...

24 October 2014 2,021 20 View

Are we testing the impact of medical drugs on the health of gut microbiota?

The current research is showing a great impact of gut microbiota on human and animal health. The question is: "Are we developing methodologies and approaches that enables us to test impact of...

01 January 1970 2,425 5 View

Is Self-organization and Emergence in Biology and Medicine Interesting subject for You?

Dear Colleaugues, There was a proposal of a researcher who asked me to write down a paper which will more or less extend the poster (link bellow) published at ICCB 2016 in Prague. This all...

01 January 1970 7,948 10 View

How to plan sample size for a crash prediction model?

Can somebody help estimating how many analysis units (number of railway level crossings - RLCs) will I need to build a crash prediction model (safety performance function)? From some past analyses...

01 January 1970 3,615 3 View

How to compare two groups with only two measurements?

Hiiiii everyone! I have an enquiry on statistical analysis. I was looking for many forum and it's still cannot solve my problem. I want to compare means of two groups of data but only with two...

03 March 2021 8,796 3 View

What's the best way to measure growth rates in House sparrow chicks from day 2 to day 10?

What's the best way to measure growth rates in House sparrow chicks from day 2 to day 10? Since, the growth curve from day 2 to 10 won't be like the "Logistic curve" it might not follow logistic...

03 March 2021 1,401 3 View

How to increase a model accuracy ?

dear community, my model is based feature extraction from non stationary signals using discrete Wavelet Transform and then using statistical features then machine learning classifiers in order to...

03 March 2021 6,994 5 View

1. What is the impact of having different scales in a survey? and how can we solve this problem before and after data collection (Literature)?

1. What is the impact of having different scales in a survey? and how can we solve this problem before and after data collection (Literature-based reflection)? Thank you for your time and for...

03 March 2021 2,870 3 View

What degree of missing data in a particular case/participant results in Expectation-Maximisation no longer working?

I'm dealing with a mediation model and am using the PROCESS module in SPSS. Due to SPSS and PROCESS being limited in the imputation methods - being unable to handle multiple imputation - the other...

02 March 2021 4,362 1 View

Can NFL theorem be valid in infinite search space in ML?

NFL theorem is valid for algorithms training in fixed training set. However, the general characteristic of algorithms in expanded or open dataset has not been proved yet. Could you show your...

01 March 2021 1,189 3 View

Does anyone know how to plot my station to a section plot on Ocean Data View (ODV)?

I made a vertical section plot with WOA .nc file on ODV, and now I want to plot my stations (csv. file) in it. Does anyone know how to import my points to the section? They are two different...

01 March 2021 3,610 1 View

How to address this issue in the analysis of Real-Time PCR results?

To dear Researchers, I was analyzing a series of concentration for estimation of Real-Time PCR efficiency. The concentration was 1:10. I used MS-excel to evaluate Slope. The result of slope was -8...

01 March 2021 8,683 4 View

How to arrange coordinates and extract climate dataset out of MPI-ESM-MR netcdf files?

Have a nice day everyone, I'm stuck in extracting datasets out of MPI-ESM-MR netcdf files because the latitude ranges from -3*10^6 to 3*10^6 and longitude ranges -5,9*10^6 to 5,9*10^6. Plus, the...

28 February 2021 912 3 View

Is there any Machine Learning/AI algorithm that lets you predict with incomplete features without missing value imputation process?

For instance, the model is trained with A,B,C,D,E features to predict F target. Then, I want to make prediction on a new data, but with only A,C,D,E is known without doing missing value imputation...

28 February 2021 1,556 6 View