We have done an invivo assay of the naoparticles that could target tumor tissues. How we can demonstrate targeting efficacy in vivo?
Label your nanoparticle with dye (such as cy3). Post injection, get
fluorescent imaging pictures via In Vivo Imaging System.
We are trying to design the multifunctional bioplymeric matrixes with fluorescent properties.
06 July 2018 8,218 3 View
We have checked ROS and mitochondrial membrane potentials integrity but need one more experiment to see the effects of our nanoparticles on mitochondrial ROS.
06 July 2018 6,946 1 View
we are evaluating the effect of natural products on wound healing in mice.
06 July 2018 804 0 View
We have synthesized a hydrogel matrix in which our drug is encapsulated.But the drug release is not satisfactory.Can anyone suggest how to increase this release efficacy?
06 July 2018 1,809 4 View
We want to evaluate the biosafety of the nanoparticles from biochemical biomarkers' detection results, for example, ASN, AST, UCN, etc in invivo system.Suggest some protocols to do this.
06 July 2018 7,799 0 View
Hello, I am currently having problems with RNA extraction. I am using mouse liver (C57BL6J), and I have extracted RNA from mouse liver before. Before this experiment, my final RNA pellets were...
11 August 2024 7,082 3 View
I am using Rhodamine6G as gain medium and silver nanoparticles as scatterers on a microscope slide and laser input 532 nm comes from above.
09 August 2024 9,894 2 View
Can anyone share any reference that gives mouse specific CD3 antibody sequence. I have been searching for this since few days and no luck. Thank you very much
08 August 2024 9,157 4 View
A fungal strain was treated with nanoparticles. We want to do an environmental SEM analysis. So could anyone share your views on preparing the sample? Thank you.
07 August 2024 5,307 1 View
Hello everyone, I have recently started using the microtome device for sectioning of paraffin-embedded mice lung. While I had some success in sectioning and observing proper ribbons, some of my...
06 August 2024 666 4 View
Hi all, I was just wondering if anyone has experience with multiplexing a mouse monoclonal primary and a rat primary. I'm trying to multiplex by incubating them in the same well but was told by a...
06 August 2024 9,710 1 View
i have sorted anti-NP specific plasma cells from bone marrow of C57BL/6 mice at certain times after immunization with variable counts and isolated total RNA using TRIZOL method for RT-PCR using...
05 August 2024 8,835 1 View
After immunohistochemistry of previously fixed in PFA and EtOH and then frozen 20 μm sections of zebrafish brain, DAPI staining is very weak (right) compared to the same sections stained without...
05 August 2024 9,637 2 View
I am working on Abaqus/Explicit(Quasistatic ) for the deformation of the auxetic structure model. Please explain how the plastic input value should be considered from the true stress-strain curve...
05 August 2024 454 3 View
A Markov-like Model for Patient Progression" Markov Chain Monte Carlo (MCMC) Markov Chain Monte Carlo (MCMC) is a powerful computational technique used to draw samples from a probability...
05 August 2024 10,079 0 View