How we can find a DNA binding region/domain/motif for any Transcription factor?

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Suhong Sun

using co-IP

Frederic Lepretre

Hi Ayesha,

bioinformatics tools could help you. test this site:

http://bioinfo.lifl.fr/NF-KB/

fred

Ramy Elgendy

Hello,

You can use the following tools to help you find the 'putative' (because it is a prediction) transcription factor binding sites:

- MatInspector (You can get 1-week free trial) https://www.genomatix.de/online_help/help_matinspector/matinspector_help.html

- TFBIND (Free tool) http://tfbind.hgc.jp/

- PROMO (Free tool) http://alggen.lsi.upc.es/cgi-bin/promo_v3/promo/promoinit.cgi?dirDB=TF_8.3

Hope that helps!

Feng Yan

Try JASPAR and TRANSFEC database.

Aziz Khan

I'll recommend to use JASPAR too http://jaspar.genereg.net

Faisal Bin Ashraf

I'll recommend to see this: Article MFEA: An evolutionary approach for motif finding in DNA sequences