A friend of mine wants to generate a marker for a disease for that she needs to go for gene polymorphism studies so how can she take the sample size for both control and test samples.
I want to check the serum and protease stabilty of a cationic peptide can I go with native gel electrophoresis other than HPLC. Just to see fragmentation if it's not stable. If someone have done...
31 December 2015 5,463 6 View
I have one cationic peptide and I want to check it's stabilty in vitro by treating it with various proteases such as elastases, Trypsin etc. Want the protocol to do this by SDS PAGE. Thanks and...
31 December 2015 6,716 13 View
I want to know more about Mn deposits in west of Afghanistan.
07 August 2024 3,427 1 View
I received an e-mail invitation to join the editorial board of Clinical Cardiology Updates. While I have published a few articles related to cardiovascular disease, there are lots of colleagues...
06 August 2024 8,981 8 View
I aim to be as skeptical as possible regarding whether a pair of orthologous genes results in the same phenotype in their different but related bacterial organisms under similar environmental...
05 August 2024 6,787 4 View
I am performing ligation of the plasmid and a target gene. The steps I have taken are: 1. Double digestion of the plasmid and target gene 2. Ligation of the plasmid with the target gene 3....
05 August 2024 2,570 3 View
I have a theoretical framework for preparing a interview guide to assess the unmet care needs of a sub population of chronically ill patients and their caregivers(dyadic interviews).
04 August 2024 8,798 7 View
average particle size calculation from TEM
04 August 2024 2,921 1 View
I am following Hainmueller, Hopkins, and Yamamoto's (2014) paper for my randomized conjoint experimental data analysis. The link to the paper is provided below. I received a comment from the...
02 August 2024 4,406 0 View
I have an RNA-seq data that I have analysed using Limma-voom and have extracted the gene IDs, log2FC and the p-values. At p value < 0.05, I have over 10,000 DEGs, however, when I run the GO...
31 July 2024 225 2 View
I am currently working on a project involving liposomes and need to determine the maximum volume of siRNA that can be added to a 2.5 mL liposome solution with a total lipid concentration of 10...
30 July 2024 6,420 1 View
I am conducting my research regarding blood coagulation in patients with CKD. I observed a reduction in post hemodialysis aPTT and PT values compared to pre hemodialysis values. But most of...
30 July 2024 3,467 0 View