How to tackle the frame shift?

01 May 2014 1 7K Report

Can someone help me regarding the frame shift? During BLAST similarity search (blastx) of sequence, I have observed +2 and sometimes +3 frames. For NCBI sequence submission, frame shift is not acceptable until someone has evidence that this protein is translated. Can anyone guide me to get rid of frame shift issue?

Grant Gallagher

Hi Abid. Can you help us by giving some background please?

thanks

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