I'm investigating the use of new recombinant/synthetic peptides in diagnostic platforms. Recently, I started using biotin-fused peptides, but I can't predict their structures by most software (i-tasser, swiss-model, rosetta).
Rob Keller
Dear Meydson Corrêa ,
Interesting question. Like you I was unable to find a prediction method for this purpose. Perhaps the following paper is of interest to you, with an interesting approach and good references:
Bräuer, M., Zich, M. T., Önder, K., & Müller, N. (2019). The influence of commonly used tags on structural propensities and internal dynamics of peptides. Monatshefte für Chemie-Chemical Monthly, 150(5), 913-925.
https://link.springer.com/article/10.1007/s00706-019-02401-x
Best regards.
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