PEG and drug loading on selenium nanoparticles?

I have coated my SeNPs with PEG and paclitaxel drug. It was characterized using UV, to check for coating by absorbance peaks.I absorbed a shift in the peak. Is there any possible explanation to...

21 November 2018 3,328 3 View

Does tumor studies in animal require 3 independent experiments done in 3 separate times?

I was having a discussion with my colleague regarding the idea of independent experiments. Is it that every mice with a distinct tumor an independent experiment or does independent experiment mean...

29 October 2018 6,949 2 View

In the absence of laboratory test or field data, how can we determine the value of coefficient of consolidation for analytical methods?

My research involves comparing the results of finite element analysis ( using ABAQUS) with analytical results. The problem is drain induced consolidation in embankments.

15 September 2018 1,254 3 View

How do we calculate the Trees correction coefficient (alpha) for Mn2+ in a d5 configuration?

I'm trying to calculate the spectroscopic parameters for Mn2+ doped ZnAl2O4 such as B, Dq, etc. For this, and to solve the Tanabe Sugano matrix, I need to compute the Trees correction coefficient...

10 May 2018 2,708 2 View

How to increase yield of green synthesized nanoparticles after centrifugation.?

I am working on green synthesis of selenium nanoparticles, the yield of the nanoparticles is very low after sonication and centrifugation. can you suggest ways to increase the yield?

14 September 2017 4,227 6 View

NASA is planning "touching the sun". How close to Sun can life "in any form" exist?

04 June 2017 885 2 View

What are the differences in cell functionality assay between reverse transfection and standard forward transfection protocols?

I am currently having problems performing my cell functional assays since when I reverse transfect my cells (HUVECs) my knockdown displays high cell death. In contrast when I transfect them by the...

18 February 2015 1,023 8 View

At what position does sgRNA cleaves in human or any organism DNA?

SgRNA is a genome editing tool which has been predominantly used for genome editing and recently integrated with Cas9 system. It would be really great if you could tell me at what place site does...

29 September 2014 6,800 7 View

What are the current views and thinking on Physical Reality and Physics?

18 September 2014 3,827 16 View

Does quantum field theory resolve the measurement problem in quantum mechanics?

Recently I read a paper titled "Quantum field theory solves the problem of the collapse of the wave function" by Alexey V. Melkikh (arXiv:1311.0205v1 - quant-ph). An earlier paper on the same...

01 September 2014 8,867 41 View

Looking for Materials with high thermal expansion coefficient and high temperature resistance?

03 March 2021 8,272 1 View

What solvent can I used for Paal Knorr reaction between 6-amino hexanoic acid and 2.5 hexanedione?

I am try to make the Paal Knorr reaction between 2.5 hexnedione and 6-amino hexanoic acid, my problem is type of solvent to use, because 6-hexaminohexanoic acid is soluble in water but I am not...

02 March 2021 4,443 2 View

How to grow E.coli on the low salt LB agar plate with 50 or 100ug/ml of Blasticidin?

Hello, I would like to ask how to grow E.coli which resists 50 or 100ug/ml of Blasticidin. I have tried many methods by using low salt Luria-Bertain(LB) agar plate. However, no colonies grow. Let...

01 March 2021 2,027 2 View

Is CD44 degraded in lysosome together with hyaluronan after CD44 mediated endocytosis of hyaluronic acid?

Also when RHAMM binds hyaluronic acid, they get internalized, will RHAMM also be degraded? Or both CD44 and RHAMM will be transferred back to the cell membrane? Asking for breast cancer cell line...

01 March 2021 8,169 2 View

How to size battery banks?

I am designing a small grid connected solar PV power-plant. As the battery's capacity is specified in Ah and demand in kWh. What is the best way to size the battery bank? I have battery price in...

28 February 2021 1,638 3 View

How to model the battery pack in PSIM or PSCAD?

Hello, I have simulated a single battery cell using Thevenin equivalent circuit. For a battery pack, I have a large number of cells connected in series and parallel connections. Is there any way...

28 February 2021 2,116 1 View

I want to performe MALDI-TOF MS for bacterial identification, I would appreciate it if anyone can tell me the matrix solution preparation protocol ?

based on what I've studied on multiple papers, for peptide and protein identification Alpha-cyano-4-hydroxycinnamic acid (CHCA) is an appropriate matrix to use, I also know that the CHCA powder...

26 February 2021 6,799 3 View

How to calculate battery consumption for IoT device?

Hi, everyone I'm working on a privacy-preserving algorithm that will apply to IoT devices. So, I need to measure the power consumption by implementing this algorithm. Any suggestion, advice,...

25 February 2021 8,749 6 View

Are there lab markers/pens resistant to Roti-Histol?

Hi, I'm looking for a pen/marker to write on the smooth, transparent (non-frosted) part of microscopy slides which does not get washed away by alcohols and most importantly Roti-Histol. I want to...

24 February 2021 9,902 5 View

How to delaminate copper in water-based anodes?

Hello everyone, I'm looking for a way to delaminate copper current collector of water-based anodes in Li-ion batteries without damaging the graphite film. I tried different materials such as HNO3...

24 February 2021 3,785 3 View