I am trying to see if hydrogels can be made using PEG functionalised with carboxylic acid in contrast with the DA functionalised hydrogels. I am hoping these modified hydrogels will have free COOH groups within its pores.
PEG (polyethylene glycol) can be functionalized with carboxylic acid groups through various chemical reactions, such as esterification or amidation. This would result in PEG chains with COOH groups attached.
Yes, hydrogels can be made using polyethylene glycol (PEG) functionalized with carboxylic acid groups. To create a PEG-based hydrogel with carboxylic acid functionality, you would typically follow these steps:
The resulting hydrogel will have carboxylic acid groups incorporated into its structure, which can be used for various applications, including drug delivery, tissue engineering, and as matrices for biological assays. The presence of carboxylic acid groups can also allow for further functionalization or modification to impart specific properties to the hydrogel.
Rajaiah Alexpandi Balram Lohan Thank you so much for your input. It was very beneficial. Will you point me towards some literature regarding the same?
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