I want to create a mutation count matrix from an expanded vcf file. I tried the genCountMatrixFromVcf() from signeR package. I am getting the following error, and I can't find any other function to create mutation count matrix.
mutcounts
I am running a coarse DNS case for pipe flow with 2.1 Million cells. My residuals are quite fluctuating as its a fully turbulent annular pipe flow case but its getting statistically converged to a...
29 May 2024 2,063 5 View
I am trying to run a turbulent pipe flow simulation with turbulent Reynolds number of 600, for 15 seconds, the flow is pressure driven due to gravity enforced buoyancy force which gives kinematic...
20 May 2024 5,619 3 View
sodium ion battery is not taking higher current when charging and also has a high voltage drop
06 May 2024 3,182 1 View
In most common turbulence model studies, when considering Reynolds stresses the components of auto-correlation, , , and components of cross-correlation are considered. In the research studies...
02 May 2024 2,776 2 View
I am planning to work on different water bodies of Andhra Pradesh. So I want to purchase a portable water testing kit with multiple parameters. Please suggest me a few best option, which would be...
17 April 2024 7,210 3 View
I need a research topic related to recent trends in GST
16 April 2024 1,805 0 View
I am working on WMLES (wall Modelled LES) for which if I calculate my wall shear stress analytically and want to enforce it as a boundary condition at the wall patch, so that I do not need to...
15 April 2024 9,059 3 View
Is there any specific relation between Re_b (bulk/ Mean Reynolds number) and Re_\tau (friction Reynolds Number). In few of the literature and experimental work I have gone through researchers give...
01 April 2024 861 5 View
This is a code block from nutWallFunction library in OpenFOAM where in, effective kinematic viscosity ($\nut_w$) at the wall is calculated using resolved field(in case of LES)/ mean field(in case...
04 March 2024 9,548 2 View
I am trying to predict the stability of a protein with different SNP. I tried using DUET, Predict SNP and Dynamut. The problem with DUET is that I cannot do double mutation however, it gives fast...
29 February 2024 2,758 3 View
PeptiCloud (www.pepticloud.com) is a bioinformatic platform that allows researchers to organize and share their data for their projects as well as collaborate with others in one place. Through...
28 July 2024 4,762 2 View
> library(meta) Error: package or namespace load failed for ‘meta’ in loadNamespace(i, c(lib.loc, .libPaths()), versionCheck = vI[[i]]): there is no package called ‘numDeriv’
18 July 2024 3,536 0 View
Hey! I aim to generate a transgenic knockin zebrafish line that mimetizes a genetic condtition that leads to a certain disease on human. To do so, I need to insert a codon for mutagenic aminoacid...
14 July 2024 6,240 0 View
Studying a specific monogenetic disease based on mutations in different individual genes. I try to recreate the disease phenotypes of donors in vitro. I knocked out a gene x with above 90%...
12 July 2024 6,313 0 View
What are the reasons why we need to practice proper post-harvest handling including packaging, after harvesting fruits and vegetables?
02 July 2024 9,999 2 View
How is active packaging as a method of preserving fruits and importance of handling packing of fruits and vegetables in prolonging their life and maintaining their quality?
02 July 2024 2,796 2 View
How can contexual bandits (used in Recommendation Systems) be implemented in code via library package ?
18 June 2024 3,196 6 View
I'm currently working on a project involving group-based trajectory modelling and am seeking advice on handling multi-level factors within this context. Specifically, I'm interested in...
16 June 2024 8,765 0 View
I have done site-directed mutagenesis (Substitution) to obtain a Cysteine mutation in my gene of interest. Now, I have two domains in my protein, And I want to delete one of the domains to obtain...
05 June 2024 9,430 1 View
I want to analyze some images (nearly 1000) in a loop. I want to analyze HSV and RGB. I have masked those images in ImageJ, which is binary masked. I tried to explore them in R, but all the...
04 June 2024 5,098 1 View