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We have multiple cell lines from different sources. We want to standardize a cell line authentication process for all existing and new incoming cell line.
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I am looking for tools/methods for somatic variant calling for unpaired samples. The somatic variant calling through GATK best practices is specifically for tumor/normal paired samples. My study...
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I have a genotype gvcf of significant size, which is causing an issue in analysis. I was wondering if there is a way to get around the size issue and run the genotype gvcf in R or do I need to...
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I want to create a mutation count matrix from an expanded vcf file. I tried the genCountMatrixFromVcf() from signeR package. I am getting the following error, and I can't find any other function...
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I want to compare the damage based on the number of hotspots for damage. Can i use two different templates each with different hotspots but both for the same sample?
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After extracting mutational signatures observed in a dataset of SNVs. I want to determine which COSMIC signature does the extracted mutational signature is close to.
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