How to change the protein chain names X into A, B, C, D after MD simulations in Gromacs?

I am running MD simulations for holoenzyme in Gromacs. The protein has four chains like A, B, C, D. After MD simulations, All the chains are showing as X chain in VMD and even in the PDB file....

12 November 2020 6,228 1 View

How to filter few markers from a gene set?

I am not good in bioinformatics. I have a gene set which has some 1000 genes which are highly correlating with aging. I want to select some highly significant genes from this geneset for further...

04 November 2020 5,602 5 View

Correlation plot between Gene of Interest and miRNA?

Please suggest portals to retrieve normalized-quantile expressions of micro-RNAs (in RPM).My aim is to construct a correlation plot between the gene of interest and microRNA. I searched in human...

28 October 2020 6,398 3 View

I am trying to do an article on domestic migration. Can anyone suggest me a research gap area where I can do my research on?

We have seen statistically that the domestic migration of workers are increasing every year. People are moving from rural to urban areas for better work and life. This migration has brought in...

03 March 2020 5,445 4 View

How will artificial intelligence help to develop MSMEs ?

Artificial Intelligence is progressive and has wider impact on various sectors. I would like to know how AI is impacting Micro, Small and Medium enterprises. The ways in which it is enacting for...

30 January 2020 7,367 3 View

What will be the perfect markers to differentiate Neural Stem cells from differentiated Neurons?

I've been working on differentiating Rat fetal Neural Stem cells into Neurons with a drug of interest. The Problem here for me is I have used various Neuronal markers like MAP2, TUJ1, NFM to...

15 October 2019 7,114 5 View

Autophagy: After how many days of fasting does autophagy usually start?

Hi, Could you please help me to explore after how many days of fasting does autophagy actually start in (1) Humans (2) Animal models and/or (3) cell lines, please? Thank you in advance

30 June 2019 8,778 5 View

Is there any standarad method or procedure for estimation of water productivity or water use efficiency of integrated farming system?

In integrated farming system (IFS), water applied for one component is also utilized in another component. So how we can compute the WUE and Water productivity of any IFS?

01 April 2019 7,555 2 View

Why the SOD1 mutant model expressing the mutant protein but not the native protein?

I am working with drug activity on familial ALS model cells. I am using mouse Neural stem cells which express the mutated human SOD1 protein. I did western blot with the protein extracted from the...

14 March 2019 511 3 View

EIS/ not stable OCP/Tafel corrosion?

Dear Researchers, I am working on titanium alloy metal corrosion resistance. I am running EIS (10e5 to 10e-2) and Tafel plot. but my OCP is not stable even after 10hrs. I have done plasma arc...

06 December 2018 8,624 4 View

Does anyone know HRM channel in a 2 plex QIAGEN Rotor- Gene Q qPCR can be used as a separate channel?

I am going to have 3 different probes in my qPCR work that I am going to do. But I realized that the machine we have in the lab is a Rotor-Gene Q 2plex HRM Platform, saying it has green, yellow,...

01 March 2021 8,544 1 View

How the Ground Plane implantation is performed without damaging (and w/o varying the undoped nature) the top Si (8-10 nm) in FDSOI technology ?

It is a general practice to introduce Ground Plane in FDSOI devices under the BoX. The Ground Planes are introduced by Ion Implantation through Top Si layer and Buried Oxide. I wanted to know that...

24 February 2021 5,974 4 View

Any references about insects or animals that can damage or weathering of rock or fossil material?

Are there any references to insects or animals that can cause damage or weathering to the rock or fossil material? books or paper that would be nice. Thank you very much!

24 February 2021 6,805 3 View

Historical wind data/map?

Hello All, I am looking for the historical wind data/map (mainly the year 2020-2021). I would like to look at the wind value and direction for the specifics locations within the US for the...

18 February 2021 9,543 4 View

Any way to separate out fluorescent channels from a composite image?

Hi there, I've been using the EVOS Auto II microscope for some time now and usually I will save the transmitted light/bright field image and the images from fluorescent channels as separate...

15 February 2021 546 3 View

Please, How can I plot a channel capacity of MIMO and SISO in matlab?

CSISO= f(frequency) : plot(f, CSISO) ? CMIMO= f(frequency) : plot (f, CMIMO) ?

13 February 2021 5,225 4 View

The reason of PMMA channels cracking?

07 February 2021 3,663 2 View

How can I reduce run-to-run variation in TMT MS experiments?

I planned an experimental setup using 10-plex TMT with 9 conditions and 1 bridge channel to compare 5 replicates. But since I experienced some run-to-run variation, I was wondering if a better...

31 January 2021 3,405 3 View

What method should I use for time-varying signal analysis?

Hello! We have a project where participants engaged in reading, thinking and then responding to an ethical dilemma. We used the EMOTIV 14 channel headset to track brain activity. The reading,...

29 January 2021 4,182 3 View

What is the best GIS tool to calculate connectivity score for a point along aquatic network?

Hello, I am looking for a GIS tool (ArcGIS, QGIS, R, etc.) that will calculate a measure of habitat connectivity for nodes along an aquatic (estuarine) network? My dataset is comprised of a...

12 January 2021 6,107 2 View