How to estimate lignin by acid detergent solution?

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In Discovery studio after loading my docked protein ligand complex, it says no ligand molecules were found. how to solve this?

This is occurring after uploading the pdb file of docked protein ligand complex from auto dock.

02 April 2024 4,328 3 View

Very slow growth of cancer cells following transfection, any suggestion to speed them faster?

Hi all, My gene causes the cancer cells to grow very slowly when it is overexpressed. Is there a method to make the cells move faster?

29 March 2024 6,021 1 View

How to convert .VSI video files to avi or mp4 presentable file?

Hi, I have captured a few videos using an Olympus microscope in a .VSI format. I wish to convert them in .mp4 or .avi file. I seek suggestions from the platform how to do so. Thank you in advance.

22 December 2023 8,124 1 View

NLS independent Nuclear localization of GPCR.....Possible or not?

Dear All, Is it possible for a GPCR to localize in the nucleus in its inactive conformation, even though it is devoid of Nuclear Localisation Signal (NLS)?

03 July 2022 2,583 2 View

How can we use deep learning to fit an N2 dimensional matrix from an N3 dimensional matrix?

The data set is the three-dimensional and two-dimensional coordinates of N pairs of points, with the three-dimensional coordinates (X1,Y1,Z) as input and the two-dimensional coordinates (X,Y) as...

14 October 2021 7,859 3 View

How does deep learning accurately fit 3d to 2d coordinate mapping?

I have a data set with three columns of input and two columns of output. I train a model through the deep learning network. According to the three columns of input, two columns of output data are...

12 October 2021 2,116 5 View

How can I create a phylogenetic tree using 182 whole genome sequences?

I have 182 whole-genome sequences including 181 reference genomes and a genome sequenced us, I would like to draw a phylogenetic tree using these 182 whole-genome .fasta files. I tried with MEGA X...

03 July 2021 4,893 4 View

Which are the best stress biomarkers that can be used to evaluate concern regarding fall among elderly?

The other tools used will be Demographic data : including life style diseases, history of fall, medications Fall Efficacy Scale- International (FES-I) Physical Performance: Short Physical...

01 February 2020 1,606 3 View

What are the samples that shows positive confirmation for ninhydrin test?

Is we have any raw sample extract that show positive confirmation in ninhydrin test?

12 February 2019 4,801 6 View

What were the main plant morphological characters considered during molecular phylogenetic studies?

Plant Morphology versus Molecular phylogeny

08 October 2017 2,501 9 View

Separation of organic acids-HPLC?

Hello What should be done to separate and identify organic acids in HPC when their RetTime is the same?Like oxalic acid with Propanoic Acid.or acids that have a very close RetTime.

07 August 2024 8,782 3 View

Determining the worth of a point improvement in Hamilton Depression Scale?

Dear readers, Thanks for your attention. I am wondering about the health economic problem of quantifying the value of interventions which a) prevent, b) improve symptom profile and c) ultimately...

05 August 2024 3,246 1 View

Conjugation of PEG-Amine to an Amino Acid Using EDC?

I am attempting to conjugate PEG to an amino acid at the C-terminus, for the purposes of producing nanoparticles. I have been told that PEG modified with amine groups can be used for this purpose,...

31 July 2024 2,033 1 View

Is the black sediment consider as sand? If not, how can I filter it out?

Hi researchers! I'm working on soil texture analysis, and the end result for sand is doubtful because there is black sediment appearing after drying, as shown in the figure. Is it considered sand?...

30 July 2024 557 2 View

Is it possible to use a safer acid instead of monochloroacetic acid to convert bacterial cellulose to carboxymethyl cellulose?

Hi, researchers, Is it possible to use a safer acid instead of monochloroacetic acid to convert bacterial cellulose to carboxymethyl cellulose?

29 July 2024 4,570 0 View

My cfDNA extraction protocol using silica beads works with plasma collected in COD SAGM bags but not with plasma collected in K2 EDTA tubes. Why so?

I am currently performing cell-free DNA (cfDNA) extraction from plasma using an in-house developed kit that employs silica-coated magnetic beads. My protocol works effectively with plasma obtained...

28 July 2024 3,559 0 View

What is the Principle of Cysteine-carbazole-sulfuric acid reaction with glucose?

I have been looking for the principle of Cysteine-carbazole-sulfuric acid reaction in research papers and books, but couldn't find it. This reaction is mainly used for the quantification of...

23 July 2024 3,891 0 View

Can we isolate microplastic from sludge sample without using vacuum filter..?

isolation of microplastic from sludge sample using centrifugation ..

23 July 2024 6,418 0 View

Can sulfuric acid be used to prepare anthrone reagent when it has oxidized and changed color in reaction to light?

Sulfuric acid has changed color to yellow.

16 July 2024 6,964 0 View

Qiagen circulating nucleic acid kit poor yield?

Hi, Attempted to extract cfDNA from a 4 mL plasma sample, with poor yield. Went through the manual in the section regarding poor yield, and feel that this does not apply. Some potential...

14 July 2024 7,475 1 View