Hi,

I have a series of quantitative MRI images (T1, T2, and myelin water fraction maps) for both patients and controls. I want to do a whole brain vowel wise analysis but am not sure what would be the best software to use. SPM12 is what comes up a lot on google but it seems like its built for functional images. My current idea would be to just brute force it with a MATLAB script to calculate Z-scores. Are there any programs that is already made for this type of analysis?

Thanks